A natural reaction to the pandemic influenza virus - an ideal model, suitable for a universal flu vaccine. According to Live Science, researchers specifically examined the changes in the immune system caused by constant exposure to the virus of influenza. Analysis was applied to blood samples from 40 people 35-70 years of age.
People are faced with two strains of the pandemic virus (H2N2 - in 1957 and H1N1 - in 1977), had elevated levels of immune proteins - a broad spectrum neutralizing antibodies. These antibodies attack the part of the virus, called a "trunk". It differs only slightly depending on the strain. But the "head" of the virus changes frequently. If you find a way to increase the concentration of these antibodies, you get a new vaccine against influenza.
However, such antibodies do not normally produced in large quantities when in contact with the seasonal influenza. The body realizes that it is now important to produce antibodies that attack the "head" of the virus.
And only if the virus is very different from the previous ones by the structure of the "head" (it comes with a pandemic strain), the body begins to increase the concentration of neutralizing a broad spectrum of antibodies that work against the "trunk". The aim - to create a vaccine conditions similar to those that are added when pandemic influenza.
The highest concentration of neutralizing antibodies in humans was facing more than one pandemic. If a person is in contact with H2N2, and H1N1, the figures are higher by 3.8 times compared to a person, only bolevshim H1N1.
The level of antibodies targeted at the "head" of the virus, eventually grew - despite the fact that the contact with the pandemic virus was only once. From this, scientists have concluded that immunity to this strain of flu remains active for a long time. And in fact, the body is constantly enhances protection against strains with which the person met.
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