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    Thursday, 31 October 2013 13:55

    Antibodies produced from seropositive, can form the basis of treatment of HIV

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    Figure1-teratoma-formation-embryoid-body-formation-snl-feeder-pluripotency-markerA powerful mixture of antibodies fighting against the AIDS virus attack pulls strong form of the virus in monkeys and then " hold off " weeks , Reuters reported , citing a research team of the U.S. government , led by researchers at Harvard University . Experts have presented findings from two studies in this direction in the journal " Nature "

    Researchers found that the rare antibodies produced by 10 to 20 percent of people with HIV, such as to counteract many of the strains of the virus. Such antibodies adhere to those areas of the virus, which are critically important to him, and which are monitored in any strain of HIV. And are attached to the virus , the antibodies do unable to infect other cells.

    In the past decade, scientists have tried to develop a vaccine that can cause the body to produce this type of specific antibodies to HIV , but it was quite difficult.

    Scientists describe the above antibodies as Ferraris antibody indicates Dr. Dan Baruch , a professor at the Medical College of Harvard University , participated in the research.

    For the purpose of both research scientists experienced antibodies on monkeys of the species rhesus infected monkey version of HIV. Rare antibodies were collected from HIV -infected people were then grown in large quantities in the laboratory and were infused in large doses to monkeys. Researchers tested various combinations of antibodies in 35 monkeys. Best working antibody called PGT 121 . Alone or with other antibodies , it gives great results.

    Generally antibodies reduced the virus to very low levels in 16 to 18 monkeys within seven days, and this effect was maintained for up to three months. In three animals carry the virus, but in small quantities after treatment he did not reappear.

    The effect of the antibodies to be tested on humans. Furthermore, it has not been studied in combination with antiretroviral drugs, which are the standard anti-HIV drugs, used by many thousands of patients in order to control the virus.

    According to scientists, however, the combination of antibodies with antiretroviral drugs would make sense because the two treatments have different mechanisms of action. Antiretroviral drugs only attack the mechanism of HIV virus to create copies, while antibodies can directly attack the particles of the virus in blood and in cells that are infected with the virus.

    It is not clear whether the antibodies can attack the dormant HIV cells that are hidden in the body and allow the virus to reappear when treatment is discontinued.

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