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GENTAUR Europe

 GENTAUR Europe BVBA
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45 
Fax 0032 16 50 90 45
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Gentaur Bulgaria

 GENTAUR BULGARIA
53 Iskar Str. 1191 Kokalyane, Sofia
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    GENTAUR France

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    9, rue Lagrange, 75005 Paris 
    Tel 01 43 25 01 50 
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    Gentaur London

     GENTAUR Ltd. 
    Howard Frank Turnberry House 
    1404-1410 High Road 
    Whetstone London N20 9BH 
    Tel 020 3393 8531 
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    ul. Grunwaldzka 88/A m.2

    81-771 Sopot, Poland
    Tel  058 710 33 44
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    Kuiper 1 
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    Piazza Giacomo Matteotti, 6, 24122 Bergamo
    Tel 02 36 00 65 93 
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    Tel 0911876558
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    Genprice USA

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    547, Yurok Circle
    San Jose, CA 95123
    Phone/Fax: 

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    San Jose, CA. 96123

     

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    Other countries

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    Tuesday, 15 April 2014 09:52

    Gene editing cures rare liver disease

    Rate this item
    (1 Vote)

    CRISPR is very easy to configure and customize equipmentUsing a new system of genetic editing based on bacterial proteins by researchers from MIT cured rare liver disease caused by a single genetic mutation.

    The findings described in the edition of Nature Biotechnology, provide the first evidence that the technique of editing of a gene known as CRISPR, can reverse disease symptoms.

    CRISPR, which offers an easy way to crop the mutated DNA and replacement with the correct sequence has the potential to treat many genetic diseases, according to the research team.

    Recently developed CRISPR system relies on cellular mechanism that bacteria use to protect themselves from viral infection.

    Researchers have copied this cell system for the creation of gene-editing complexes, including DNA.

    They are cut enzyme called Cas9, bound to the RNA strand, which can be programmed to bind to a specific genomic sequence.

    Meanwhile, researchers deliver DNA template strand.

    When repairing cell damage resulting from Cas9, scientists introduced the template DNA in the genome.

    Scientists predict that this type of revision of the genome one day could help in the treatment of diseases such as hemophilia, Huntington's disease, and the like, caused by a single mutation.

    There are other systems developed on the basis of genetic editing of DNA enzymes known as nucleases, but these complexes can be expensive and difficult to assemble.

    In contrast, CRISPR is very easy to configure and customize equipment.

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