RETRO-TEK kits have been designed for the quantitative measurement of viral antigens from the retroviruses HIV-1, SIV and HTLV found in cell culture, serum, plasma or other biological fluids.

Product list:

Gentaur now offers 30% discount on ELISA Kits:

Cat.	Product	Quantity	Old Price	Promo Price	Order
CSB-E15903Br	Avian Prolactin/Luteotropic Hormone(PRL/LTH) ELISA Kit	96T	600 €	462 €
CSB-E16209	Biotin ELISA Kit	96T	696 €	535 €
CSB-EQ027738BO	Bovine Adenovirus 3 (ADV3) antibody (IgG) ELISA kit	96T	696 €	535 €
CSB-EL027852BO	Bovine anti-toxoplasmosis antibody(IgG) ELISA kit	96T	696 €	535 €
CSB-EL001918BO	Bovine Apolipoprotein B (APOB) ELISA kit	96T	696 €	535 €
CSB-EL001936BO	Bovine Apolipoprotein E(APOE) ELISA kit	96T	558 €	429 €
CSB-E15919B	Bovine C-Peptide ELISA Kit	96T	696 €	535 €
CSB-E13064B	Bovine Cortisol ELISA Kit	96T	506 €	389 €
CSB-E08173b	Bovine Estradiol,E2 ELISA Kit	96T	592 €	455 €
CSB-E13074B	Bovine folic acid,FA ELISA Kit	96T	696 €	535 €

More ELISA Kits from the promotion 

From 8th to 31st of March GENTAUR’s ELISA kits of highest quality are with 30% discount!!!

Cat.	Product	Old Price	Promo Price	Order
CK-E94663	.Mouse aldosterone (ALD) ELISA Kit	615 €	430 €
CK-E90283	90283Human Soluble CD163_sCD163_ ELISA Kit	615 €	430 €
CK-E90006	ACTH ELISA Kit	615 €	430 €
CK-E90364	Adiponectin Receptor 1 ELISA Kit	615 €	430 €
CK-E94919	Aflatoxin albumin adduct Elisa kit	615 €	430 €
CK-E95548	Aflatoxin albumin adduct Elisa kit	615 €	430 €
CK-E90363	Aflatoxin albumin adduct Elisa kit	615 €	430 €
CK-E90365	Aflatoxin Elisa Test kit	615 €	430 €
CK-E90060	Aflatoxin,AFT ELISA Kit	615 €	430 €
CK-E90010	AMPK ELISA Kit	615 €	430 €

Click here to see more products from the promotion

ELISA Plate Washer is a versatile, user friendly & rugged instrument designed by keeping
both quality and price in view. The instrument is simple, yet versatile as it uses
the state of art hardware for its components.

Special Features

- Built in two plate ELISA incubator
- User programmable soak time, wash cycles and dispensing volume
- Battery backed up memory for 50 tests.
- Waste bottle full indicator with audible alarm.
- Built-in stabilizer.
- State of art equipment with versatile software.
- Real time clock.
- Continuous aspiration to prevent overflow.
- Loosely held Manifold to prevent scratching of well bottoms.
- Uses special software to aspirate “U“ shaped, ”V” shaped, and wide wells.

 Specifications:

Download Technical Sheet Specification

Price: 1716 €

Contacts:

e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ELISA Plate Analyser offered by Gentaur / GDMS is user friendly micro plate Analyser. It is compact & lightweight. It is designed to measure and interpret enzyme immunoassay results, both monochromatically and bichromatically.
It is intended for in vitro diagnostic use.

Special Features

The ELISA Plate Analyser can accommodate a flat bottom as well as a round configuration. The carriage is
designed in a way that the plate automatically moves smoothly and positions itself accurately in the
optical measurement path. Readings are taken continuously.The average value is calculated and
results are presented according to the option selected.

The ELISA Plate Analyseroperates on a WIDE voltage (90-270 volt). This eliminates the need for an
external voltage stabilizer.

The ELISA Plate Analyserhas a special provision, which allows it to be used even when a printer is not
available. Readings can be conveniently noted down manually, by using the PAUSE option.

The other special features of ELISA Plate Analyserare the following:

o Option of Lamp saving mode.
o Selection of both primary and secondary filters.
o Latest technology with battery back up for 250 tests with QC, more than 2500
result.
o Robust built in 52-column thermal printer with 384 stationary heads.
o Unique circuitry for long lamp life.
o Alphanumeric Patients ID entry.
o Editing of saved tests.
o Human machine user interface: Touch panel, Keypad
o Multi-standard curve up to 12 standard calibrations with one blank optional.
o Access to test by touch of key.
o Capability to connect to 80-column printer for direct report printout.
o Blank is optional.
o Setting of the Date and Time.
o Capable of storing, deleting and recalling tests.
o Multiple calibrator modes.
o Selection of duplicates for both calibrators and samples.

Download Technical Sheet Specification

Price: 1880 €

Contacts:

e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.">This email address is being protected from spambots. You need JavaScript enabled to view it.

Experts in the field of engineering, chemical compounds from MIT (Massachusetts Institute of Technology, MIT, USA) showed that the matrix consisting of billions of nanoscale sensors have unique properties that can enhance the safety and efficiency of various drugs, particularly drugs, based on antibodies.

With these sensors, the scientists were able to characterize the different types of interactions of drugs based on antibodies, which in the long run will help in the development of effective treatments for cancer and other diseases. The sensors can be used to assess the structure of antibody molecules and determining their content of sugar chains that prevent their functioning.

"Pharmacological method can help companies identify the reason for a certain technology of preparation of medicines work better than others, which will increase the efficiency of production", - says Michael Strano (Michael Strano), a professor of chemical engineering at MIT, one of the authors of the Nanoscale sensors, recently published in the journal ACS Nano.

According to Strano, the research team also demonstrated how nanosensor matrix can be used to determine the most productive and preferred cells in a population of genetically modified cells that synthesize drugs.

Evaluating the effectiveness of drugs

The results of previous studies conducted by countries and other scientists have shown that the use of the finest nanoscale sensors, such as carbon nanotubes, is an effective method to determine the chemical compounds present in the solution in small amounts. Carbon nanotubes are 50 thousand times thinner than a human hair. They are able to join the proteins recognize specific Targeted molecule. If the solution contains Targeted molecule fluorescent signal produced by the carbon nanotube varies and it can be detected.

For the simultaneous determination of a large number of different targets in solution, some scientists are trying to use a large array of nanosensors, in particular, carbon nanotubes or semiconductor nanowires, each of which focuses on a specific targeted molecule. In the new study, Strano and his colleagues studied the unique properties of large sensors that detect the same chemical.

The first property, scientists detected nanosensors - is that the matrix consisting of equally spaced sensors can measure the force distribution compounds arising in complex proteins such as antibodies.

Antibodies - the body naturally synthesized molecules that play a key role in the immune response. In recent years, scientists have developed antibodies to treat various diseases, including cancer. The addition of these antibodies to surface proteins of cancer cells stimulates an immune response to the tumor.

To drugs based on antibodies to be effective, they must be specifically attached to its target. However, the process of antibody production , which is dependent on engineering cells does not always lead to the production of consistently and uniformly acceding parties antibodies.

Currently, for testing batches of drugs in order to confirm their compliance with the performance standards used by pharmaceutical companies for long time and expensive analytical processes. The new sensor, developed by scientists from MIT, can greatly speed up the process, allowing scientists not only to more effectively monitor and control the process of production of drugs, but also to fine-tune their production. This will result in a more uniform product synthesized.

Measurements of weak interactions

Another nice feature of sensors is their ability to measure the weak binding interactions that can also help in the production of drugs based on antibodies.

Normally, this process of protein glycosylation antibodies surface is covered with long chains of carbohydrates which provide drug efficacy. But sugar chain is extremely difficult to detect, since they interact with weak bonds with other molecules. Organisms that produce antibodies are programmed in such a way as to connect the chain of sugars. However, this process is difficult to control, and it largely depends on the environment surrounding the cells, including the temperature and acidity.

If an antibody is introduced into the patient will not be glycosylated proteins, they can cause the development of an unwanted immune response or be destroyed by the patient's own cells, making them useless.

According to Strano, drug companies and scientists who have tried to identify glycosylated proteins by recognizing the hydrocarbon chains, experienced difficulties. "Nanosensor matrix can greatly increase the possibility of determining the rare events of joining molecules. You will be able to measure something that is not able to estimate with a large sensor with the same sensitivity, "- says the country.

The new method could help scientists determine the optimal conditions for adjusting the degree of glycosylation of proteins that facilitate the production of equally effective drugs.

The definition of the product obtained

The third property of nanoscale sensors, studied by scientists - is the ability to detect the synthesis of a molecule of interest. According to Strano, professionals want to be able to identify specific strains of microorganisms that synthesize the necessary medicines. "There are many ways to do this, but none of them is not easy," - says the country.

The research team from MIT found that culturing the cells on the surface coated with a matrix of nanoscale sensors that can help identify the location of the majority of synthesizing cells. In the new study, the researchers studied the antibodies are synthesized artificially synthesized human embryonic kidney cells. However, established engine also can be individually configured to proteins and other organisms.

According to Strano, immediately after the detection of the most productive cells, scientists are studying the genes that distinguish these cells from other cells that have a lower efficiency in the production of medicines. As a result, they create a new strain having increased ability to synthesize the desired chemical compounds.

Scientists have created a prototype of a portable sensor, which they plan to test in the pharmaceutical company Novartis. The study will be funded by Novartis and the National Science Foundation (National Science Foundation, USA).

U.S. researchers said they have achieved very good results in clinical testing of an experimental vaccine against malaria, world agencies reported.

The disease caused by the parasite each year causing 600,000 deaths, mostly among children in Africa. The vaccine is derived from a number of attenuated parasites Plasmodium fa, an infection spread by female mosquitoes of the genus Anofelesi. It is one hundred percent protection achieved in six out of nine adult volunteers who received the highest dose of it. In these primary tests involved 40 people aged between 20 and 44 years.

"Although we are in the early stages of the development of the vaccine, we are confident that our vaccine will help us to fight malaria," said Stephen Hoffman, executive director of the laboratory "Sanary" in which are held
research. They are funded by the U.S. National Institute of Allergy and Infectious Diseases and other organizations from the U.S., Europe and Africa.

Scientists 30 years trying to develop antimalarial vaccine. But only now have a very safe immunization tool that is injected and can save millions of lives, "said Hoffman.

Although extremely hopeful results, some experts are still skeptical of the small number of subjects on which it was tested the new vaccine.
For this reason, the scientific team will undertake additional clinical trials in Germany, the U.S. and Africa. Those skilled will test and a different frequency of vaccination in order to achieve one hundred percent protection against at least 5 doses of the novel vaccine.

So far, the way to extract parasites from the salivary glands of mosquitoes is quite slow and requires the efforts of 12 to 15 professionals who manage to dissect around 150 insects per hour. Another difficulty is that the vaccine must be stored in liquid nitrogen. Laboratory "Sanary" already collaborates with Harvard University to automate the process.

These laboratory studies have opponents, there is no guarantee that nature will follow the theoretical approach.

While some scholars argue that it should be kept for research purposes genetically manipulated viruses of avian influenza in several laboratories around the world are already conducting similar experiments, reported the German magazine "Focus". Several teams working in parallel with genetically manipulated virus H7N9. Ron Fucino, one of the scientists involved in the experiments confirmed that his colleagues in several places around the world already are testing resistance to drugs.

Other attempts were allegedly in the pipeline, says Fucino who specializes Flu Medical Center "Erasmus" in Rotterdam. They will study the behavior of the virus modified so as to be easily transmitted from person to person. From mid-March in China already has at least 130 people infected with the dangerous strain H7N9.

This week leading experts called in the journal "Nature" to be carried out similar experiments in which the causative agent is modified in vitro so as to be more infectious and resistant to treatment with drugs. They hope that science will overtake both real life and will be prepared to respond to any mutations in the strain of bird flu, which has threatened a number of Asian countries.

Such an approach, however, meeting and much criticism. According to the China Center for combating infectious diseases in natural mutation of a virus can take years. In the laboratory, it happened in an instant. There is no guarantee that the actual mutations will follow artificial scientific model.

According to Ron Fucino however scientific experiments are very useful and are based on actual forecasts. Attempts would make it possible to produce more effective vaccines and scientific teams would predict risks of transmission of the virus from person to person. New form of H7N9 bird flu was confirmed in humans for the first time in March 2013 Health officials believe that spillover occurred from birds to humans. Thousands of birds were killed and live poultry markets were closed. An outcome measure, the number of new infected dropped almost to zero. In April, the WHO issued a warning that in some cases the virus can be passed from person to person. Scientists from China have joined this opinion and wrote in the British Medical Journal, the risk of bird flu is by no means

In recent years, people are constantly being bombarded by mass media with threats that if you do not take vitamin D as a dietary supplement, will develop a deficit and will get sick. Only that vitamin D is one of those substances that adopted more harm. How accurate is the measure of the amount of beneficial to health?

Scientific team from the hospital, "John Hopkins" found that "sunlight vitamin" - vitamin D, taken in doses higher than normal, it provides additional advantages for health. Half an hour a day sunlight is sufficient to enable the formation of the minimum required amounts of vitamin D in the body. He also assumes the food.

According to scientists, vitamin D should be taken only on prescription. Dr. Muhammad Amer by the same research team showed that the only ones who need a slightly higher intake of vitamin D are people over 65, women undergoing or have undergone menopause and people with kidney disease. Elevated blood levels of this vitamin is mainly to promote bone health.

Dr. Amer stated that sufficient exposure to sunlight, strong bones, exclusion of vulnerable groups, the intake of vitamin D without prescription is risky for health.

Report of the American Heart Journal in 2012 found that 25-hydroxyvitamin D levels in the blood of more than 21 nanograms per milliliter not only reduce its usefulness, but also directly harm him. Such high doses are able to suppress and reduce the amount of protein bound by the Cardiovascular inflammation - C-reactive protein or CRP. This leads to loss of elasticity of blood vessels, which is a factor of increase in blood pressure and the onset of cardiac problems.

Another factor is the relationship of the vitamin C levels of homocysteine ​​- non-protein amino acid that is a factor in many cardiovascular diseases. High levels of homocysteine ​​are always available when there is a thrombus - a blood clot blocking a blood vessel and can cause heart attack, stroke or pulmonary embolism. In pregnant women is considered to lead to miscarriage and / or preeclampsia - a condition characterized by very elevated blood pressure and presence of protein in the urine. This condition can lead to eclampsia.
 
Experts advise before buying vitamin supplements to consult a doctor and make a quick blood test. Vitamin supplements should be taken according to the individual needs of everyone, because the difference between benefit and harm is only in dosage.

Due to hormonal changes occurring in women's bodies after '40, women should pay particular attention to vitamin D. Female body may procure vitamins in three ways: through food, naturally rich in vitamins and with added ones by exposing the skin to sunlight and through dietary supplements.

Although sunlight and natural foods are the best source for each age, women over 40 sometimes need to take supplements to prevent vitamin deficiency. After that age, the recommended daily dose of vitamins for the fairer sex is 15 micrograms.
 
The main foods that are rich in vitamin D include: mushrooms, fatty saltwater fish, eggs, liver and alfalfa. If it is not possible to obtain the vitamins in adequate amounts with food, it is necessary to take nutritional supplements.

25-hydroxyvitamin D supports the growth, development and maintenance of bone, helps the regulation of blood pressure and activity of the immune system by affecting cells such as macrophages and T cells. It plays an important role in cellular differentiation. Women who do not get enough vitamin D under highly increased risk of developing cancer, hypertension, osteoporosis, and autoimmune diseases such as rheumatoid arthritis and insulin-dependent diabetes.
 
The World Health Organisation recommends taking 15 micrograms of complex substances every day. Except for women over 40, this recommendation applies to pregnant or lactating mothers. In pharmacies, without prescription sell many supplements and vitamins that support the required balance, but if taken without the express prescription by a doctor can cause a number of side effects: diarrhea, vomiting, weight loss, bone and joint pain and fatigue. They can intervene in the action of drugs based on corticosteroids.

Women suffering from kidney or heart disease or high levels of calcium and phosphorus in the blood should not take supplements with vitamin D.
 
It is possible overdose of vitamins. The maximum dose that is tolerated by the body is about 150 micrograms per day. If this dose is exceeded, excess compound assumed it was too much to be removed from the body and acts as a toxin. Diseases of hypervitaminosis D, causing cardiac arrhythmias develop kidney stones, severe weight loss, kidney damage, and the walls of blood vessels, muscle weakness, and bladder problems.

Deficiency of vitamin D e much more widespread and common than overdosing because usually noticed only when they develop any of the conditions surrounding it. The reasons for the deficit are endless, but among the main worldwide are: women who lived much of north and are subjected to short days and long nights or women who cover their skin for religious reasons - and in both cases it is strongly suppressed at natural sources of vitamin D - sun. The second is obesity. Ladies overweight more likely to develop inflammatory condition of the gastrointestinal tract that often go unnoticed, but impair the absorption of vitamin coming with food.
 
You should always seek medical advice before accepting any pharmaceutical product, even vitamins.