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Voortstraat 49, 1910 Kampenhout BELGIUM
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    Monday, 29 July 2013 13:54

    Mole or cancer?

    melanoma-cf-1-gene-knock-in-technology-ipsc-generation-cell-line-gene-modification-cel-line-model-diseaseMost adults have between 10 and 40 moles on their bodies, and the distinction between innocent dark speck of a cancer is not easy.
     
    Dr. Mary Lupo, consultant dermatologist from New Orleans advises the skin of the whole body can be accessed once a month and it's not alone. This could help a close, preferably once and later as instructed to do consult a dermatologist, who can focus on certain features of the skin individually.

    On moles should be monitored for some strictly defined factors: color, position, size and integrity.

    If there is something offensive about unemployment of a mole on her should be given special attention. Pinkish spot from which or about which there is a scaly skin, not available sunburn and is usually located on the face, hands or shoulders is often the first suspect - actinic keratosis. They quickly pass. In over 20% of cases, however, these "precancerous" formations lead to squamous cell carcinoma. Patients and even dermatologists might confuse these signs of eczema, but it does not go alone with such speed.

    Speck that looks fresh pink and shiny, located on the head, neck or ears can be basal cell carcinoma. This most common type of skin cancer rarely metastasizes, but its formation are especially dangerous. Statistically, if it is an ear or lip lies strongly increased risk of spread to the lymph nodes and from there - to the lungs.

    Reddish, scaly and slightly elevated above the rest leather stain hiding potential of squamous cell carcinoma. You may have lesions - small wounds that have a high potential for metastasis and often can be fatal.
     
    Spots that are asymmetric with uneven shapes and colors, irrespective of where the body, most often a sign of melanoma - the most fatal form of skin cancer. Its formations are usually close to the size of an eraser on a pencil. Their color can be overflowing or heterogeneous and include: dark blue or dark red, deep brown and

    Published in News

    mouseThe most deadly form of skin cancer - melanoma, has its unique signature of chemicals found scientists from Monell Chemical Senses Center and the University of Pennsylvania in Philadelphia. The survey can help opening new, non-invasive method for the diagnosis of melanoma at an early stage. The discovery was published in the special report in the journal Journal of Chromatography B.

    Melanoma is the most aggressive and dangerous type of skin cancer. It is characterized by rapid growth and early spread to other parts of the body.
    Melanoma is a typical black because melamine synthesized by the cells. However, there are colorless (leuco-melanoma), in the course of their malignant tumor cell degeneration have lost the ability to synthesize a pigment. These melanomas usually more malignant than black.

    The relationship between the melanoma cells is very weak. They are easily removed from the tumor and were brought through the blood or lymph. Therefore melanoma metastasizes very early and abundantly throughout the body - regional lymph nodes, internal organs, muscles, bones, brain, and if the patient has other cancers - even in them. Likewise, melanoma cells are generally well-differentiated, which makes them less sensitive to chemotherapy and radiation therapy, and reduces the immune response against them, and this contributes to the rapid growth of the tumor.

    For his research team scientists from University of Pennsylvania used the samples grown in the laboratory melanomas in three stages of development, and healthy cells. Once individual samples proved that there are significant differences in the concentration of certain chemicals that produce odors between normal cells and those infected with melanomas.

    Researchers are even able to "see" the differences between different types of melanoma cells from detaching from their chemical signatures.

    Published in News

    FDA has approved two drugs to GlaxoSmithKline for the treatment of advanced melanoma - the most aggressive skin cancer patients with specific genetic mutations. Regulatory approvals, and diagnostic test for demonstrating these mutations.
     
    The drugs are approved for administration separately, once in two separate clinical trials, they showed delayed tumor growth.

    mouse

    After decades of virtually no progress in the fight against advanced melanoma, two new drugs celebrated turn in favor of medicine. Over the past two years, FDA has approved a total of 4 new drugs this indication.
     
    Each year in the U.S. from melanoma ill about 75 000 people. The mortality rate is around 9,000 to 10,000 per year.
     
    Forecast sales for each of the two new drugs are about 350 million dollars a year.

    Published in News