Tuberculin PPD (Purified Protein Derivative) for in vitro use is an immunological reagent for research on cellular immunity.

Quantity: 5 ml
Pharmacology
Contains soluble products from mycobacterium, which react with lymphocytes to release mediators of cellular hypersensitivity. Some of these mediators induce inflammatory response. Positive reaction is consistent with previous or current tuberculosis infection or previous BCG vaccination.
Indications and Usage
The product is used for Lymphocyte proliferation assays and induction and measurement of proliferation and cytokine production in sensitised lymphocytes.
Further the product can be used for studies on migration inhibition of monocytes/macrophages and other phagocytozing cells.
Storage/Stability
PPD multipuncture devices should be stored at room temperature. PPD solution should be stored in refrigerator.
Drug Interactions
BCG vaccine, previous:
May result in positive PPD test (see Precautions).
Corticosteroids or other immunosuppressive drugs:
May suppress reactivity to any tuberculin test.
Recent immunization with live virus vaccines (including influenza, measles, mumps, rubella, polio virus, smallpox, yellow fever):
May suppress reactivity to any tuberculin test. If tuberculin skin testing is indicated, perform it either before or simultaneous with immunization or 4 to 6 wk after immunization.
Laboratory Test Interactions:
None well documented.
Product Use Limitation
Only for research purposes - in vitro use only.






